| 2022-10-03 | Astana | Hard | R32 | 6 |  Stefanos Tsitsipas (3) | 221 |  Mikhail Kukushkin (WC) | 6-3 6-4 | H2H | 3 | 83 | 5 | 1 | 78.6% | 81.8% | 50.0% | 0/0 |
| 2022-09-13 | Davis Cup Finals RR: KAZ vs NED | Hard | RR | 48 |  Tallon Griekspoor | 221 | Mikhail Kukushkin | 6-1 3-6 6-3 | H2H | 3 | - | - | - | - | - | - | - |
| 2022-09-15 | Davis Cup Finals RR: USA vs KAZ | Hard | RR | 29 |  Tommy Paul | 221 | Mikhail Kukushkin | 6-1 6-4 | H2H | 3 | - | - | - | - | - | - | - |
| 2022-06-27 | Wimbledon | Grass | R128 | 34 | Jenson Brooksby (29) | 164 | Mikhail Kukushkin | 6-3 6-2 6-3 | H2H | 5 | 111 | 3 | 0 | 65.0% | 71.2% | 60.7% | 3/4 |
| 2022-04-18 | Belgrade | Clay | R32 | 164 | SLOAljaz Bedene (PR) | 167 | Mikhail Kukushkin (WC) | 7-6(4) 4-6 6-3 | H2H | 3 | 157 | 10 | 5 | 52.4% | 75.9% | 59.2% | 3/5 |
| 2022-03-21 | Miami Masters | Hard | R64 | 13 | Taylor Fritz (11) | 159 | Mikhail Kukushkin (Q) | 6-3 5-7 6-3 | H2H | 3 | 126 | 10 | 0 | 64.0% | 85.4% | 59.3% | 0/1 |
| 2022-03-21 | Miami Masters | Hard | R128 | 159 | Mikhail Kukushkin (Q) | 42 | Botic van de Zandschulp | 6-4 6-4 | H2H | 3 | 110 | 0 | 1 | 56.4% | 63.6% | 61.8% | 11/12 |
| 2022-03-07 | Indian Wells Masters | Hard | R128 | 39 | Tommy Paul | 154 | Mikhail Kukushkin (Q) | 6-4 6-4 | H2H | 3 | 90 | 4 | 1 | 55.4% | 80.6% | 48.3% | 2/3 |
| 2022-03-04 | Davis Cup QLS R1: KAZ vs NOR | Hard | RR | 8 |  Casper Ruud | 160 | Mikhail Kukushkin | 6-1 6-4 | H2H | 3 | 73 | 10 | 1 | 60.8% | 77.4% | 75.0% | 1/1 |
| 2022-02-14 | Marseille | Hard | R32 | 109 |  Pierre-Hugues Herbert | 168 | Mikhail Kukushkin (Q) | 7-6(5) 7-5 | H2H | 3 | 114 | 8 | 2 | 61.2% | 73.2% | 69.2% | 0/2 |
