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| # | Player | First Tournament | First Date | Last Tournament | Last Date | Timespan |
|---|---|---|---|---|---|---|
| 1 |  Novak Djokovic | US Open | 2007-08-27 | Australian Open | 2026-01-30 | 6731d (18y 161d) |
| 2 |  Rafael Nadal | Roland Garros | 2005-05-23 | Roland Garros | 2022-05-23 | 6209d (17y 4d) |
| 3 |  Roger Federer | Wimbledon | 2003-06-23 | Wimbledon | 2019-07-01 | 5852d (16y 12d) |
| 4 |  Andre Agassi | Roland Garros | 1990-05-28 | US Open | 2005-08-29 | 5572d (15y 97d) |
| 5 | Pete Sampras | US Open | 1990-08-27 | US Open | 2002-08-26 | 4382d (12y 2d) |
| 6 |  Boris Becker | Wimbledon | 1985-06-24 | Australian Open | 1996-01-15 | 3857d (10y 207d) |
| 7 | Jimmy Connors | Australian Open | 1973-12-26 | Wimbledon | 1984-06-25 | 3834d (10y 184d) |
| 8 | Ivan Lendl | Roland Garros | 1981-05-25 | Australian Open | 1991-01-14 | 3521d (9y 236d) |
| 9 |  Goran Ivanisevic | Wimbledon | 1992-06-22 | Wimbledon | 2001-06-25 | 3290d (9y 5d) |
| 10 |  Juan Martin del Potro | US Open | 2009-08-31 | US Open | 2018-08-27 | 3283d (8y 363d) |