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| Rank | Player 1 | Wins | Player 2 | Wins | Total H2H | H2H |
|---|---|---|---|---|---|---|
| 1 | 10 | 6 | 16 | Djokovic vs Federer → | ||
| 2 | 9 | 6 | 15 | Djokovic vs Murray → | ||
| 3 | 6 | 8 | 14 | Agassi vs Sampras → | ||
| 4 | 10 | 3 | 13 | Djokovic vs Nadal → | ||
| 5 | 6 | 2 | 8 | Federer vs Nadal → | ||
| 6 | 7 | 0 | 7 | Laver vs Rosewall → | ||
| 7 | 2 | 4 | 6 | Medvedev vs Sinner → | ||
| 8 | 4 | 2 | 6 | Federer vs Murray → | ||
| 9 | 4 | 2 | 6 | Potro vs Federer → | ||
| 10 | 2 | 4 | 6 | Lendl vs McEnroe → |
