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Most matches in Grand Slam in Round of 16

Rank	Player	Appearances
1	Novak Djokovic	70
2	Roger Federer	69
3	Rafael Nadal	54
4	Jimmy Connors	43
5	Andre Agassi	42
6	Ivan Lendl	42
7	Andy Murray	38
8	Pete Sampras	36
9	Tomas Berdych	33
10	John McEnroe	33
11	Stefan Edberg	33
12	Boris Becker	31
13	Lleyton Hewitt	30
14	Marin Cilic	28
15	Stan Wawrinka	28
16	Guillermo Vilas	27
17	David Ferrer	27
18	Mats Wilander	26
19	Jo-Wilfried Tsonga	25
20	Bjorn Borg	25