| 2022-04-25 | Munich | Clay | R32 | 67 |  Daniel Altmaier | 132 | Philipp Kohlschreiber (WC) | 7-6(5) 3-6 6-1 | H2H | 3 | 145 | 6 | 3 | 62.3% | 63.6% | 60.0% | 9/12 |
| 2022-03-07 | Indian Wells Masters | Hard | R128 | 70 |  Emil Ruusuvuori | 136 | Philipp Kohlschreiber (Q) | 6-3 6-3 | H2H | 3 | 85 | 0 | 1 | 66.7% | 66.7% | 50.0% | 2/4 |
| 2022-01-17 | Australian Open | Hard | R64 | 18 |  Roberto Bautista Agut (15) | 134 | Philipp Kohlschreiber | 6-1 6-0 6-3 | H2H | 5 | 88 | 5 | 1 | 56.7% | 82.4% | 69.2% | 1/1 |
| 2022-01-17 | Australian Open | Hard | R128 | 134 | Philipp Kohlschreiber | 95 |  Marco Cecchinato | 6-4 7-5 7-6(0) | H2H | 5 | 128 | 10 | 3 | 69.9% | 89.2% | 57.1% | 1/1 |
| 2021-10-04 | Indian Wells Masters | Hard | R128 | 123 |  Taro Daniel | 107 | Philipp Kohlschreiber (PR) | 6-2 6-4 | H2H | 3 | 99 | 1 | 4 | 63.4% | 66.7% | 53.8% | 7/8 |
| 2021-09-20 | Metz | Hard | R16 | 20 |  Gael Monfils (3) | 107 | Philipp Kohlschreiber (LL) | 7-6(2) 6-4 | H2H | 3 | 92 | 8 | 3 | 60.6% | 88.4% | 39.3% | 4/6 |
| 2021-09-20 | Metz | Hard | R32 | 107 | Philipp Kohlschreiber (LL) | 83 | Marco Cecchinato | 7-6(3) 6-3 | H2H | 3 | 87 | 3 | 1 | 60.8% | 80.0% | 65.5% | 2/2 |
| 2021-08-30 | US Open | Hard | R64 | 74 | Pablo Andujar | 115 | Philipp Kohlschreiber | 6-4 6-3 6-1 | H2H | 5 | 125 | 4 | 2 | 68.6% | 76.3% | 44.4% | 5/6 |
| 2021-08-30 | US Open | Hard | R128 | 115 | Philipp Kohlschreiber | 36 |  Marin Cilic (30) | 6-7(4) 6-7(3) 6-2 6-1 2-0 RET | H2H | 5 | 219 | 21 | 5 | 51.9% | 76.1% | 61.3% | 6/7 |
| 2021-07-24 | Tokyo Olympics | Hard | R64 | 4 |  Stefanos Tsitsipas (3) | 112 | Philipp Kohlschreiber | 6-3 3-6 6-3 | H2H | 3 | - | - | - | - | - | - | - |
