| R64 | 77 |  James Duckworth | 246 |  Lukas Klein | 5-7 6-3 7-6(4) | 3 | - | - | - | - | - | - | - |
| R64 | 68 |  Jeremy Chardy | 195 |  Tomas Barrios Vera | 6-1 7-6(4) | 3 | - | - | - | - | - | - | - |
| R64 | 42 |  Nikoloz Basilashvili | 90 |  Roberto Carballes Baena | 6-3 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 35 | Alejandro Davidovich Fokina | 120 |  Pedro Sousa | 6-3 6-0 | 3 | - | - | - | - | - | - | - |
| R64 | 5 |  Alexander Zverev | 573 |  Yen-Hsun Lu | 6-1 6-3 | 3 | - | - | - | - | - | - | - |
| R64 | 4 |  Stefanos Tsitsipas | 112 | Philipp Kohlschreiber | 6-3 3-6 6-3 | 3 | - | - | - | - | - | - | - |
| R64 | 2 |  Daniil Medvedev | 40 |  Alexander Bublik | 6-4 7-6(8) | 3 | - | - | - | - | - | - | - |
| R32 | 66 |  Ilya Ivashka | 123 | Mikhail Kukushkin | 6-7(4) 6-3 6-3 | 3 | - | - | - | - | - | - | - |
| R32 | 35 | Alejandro Davidovich Fokina | 44 | John Millman | 6-4 6-7(4) 6-3 | 3 | - | - | - | - | - | - | - |
| R32 | 42 | Nikoloz Basilashvili | 26 |  Lorenzo Sonego | 6-4 3-6 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 160 |  Sumit Nagal | 197 |  Denis Istomin | 6-4 6-7(6) 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 145 |  Tomas Machac | 137 | Joao Sousa | 6-7(5) 6-4 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 123 | Mikhail Kukushkin | 62 |  Federico Coria | 7-6(4) 7-5 | 3 | - | - | - | - | - | - | - |
| R64 | 28 | Ugo Humbert | 65 | Pablo Andujar | 7-6(3) 6-1 | 3 | - | - | - | - | - | - | - |
| R64 | 57 | Dominik Koepfer | 80 | Facundo Bagnis | 3-6 6-3 7-5 | 3 | - | - | - | - | - | - | - |
| R64 | 50 |  Miomir Kecmanovic | 115 |  Kamil Majchrzak | 6-4 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 64 |  Marcos Giron | 98 | Norbert Gombos | 7-6(4) 3-6 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 79 | Egor Gerasimov | 102 | Gilles Simon | 4-6 6-3 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 113 |  Daniel Elahi Galan | 171 |  Mohamed Safwat | 7-5 6-1 | 3 | - | - | - | - | - | - | - |
| R64 | 36 |  Marin Cilic | 217 |  Joao Menezes | 6-7(5) 7-5 7-6(7) | 3 | - | - | - | - | - | - | - |
| R64 | 142 |  Liam Broady | 116 | Francisco Cerundolo | 7-5 6-7(4) 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 190 | Max Purcell | 15 |  Felix Auger-Aliassime | 6-4 7-6(2) | 3 | - | - | - | - | - | - | - |
| R64 | 13 | Diego Schwartzman | 122 |  Juan Pablo Varillas | 7-5 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 12 | Hubert Hurkacz | 417 | Luke Saville | 6-2 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 11 | Pablo Carreno Busta | 81 | Tennys Sandgren | 7-5 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 69 |  Kei Nishikori | 7 | Andrey Rublev | 6-3 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 26 | Lorenzo Sonego | 110 | Taro Daniel | 4-6 7-6(6) 7-6(3) | 3 | - | - | - | - | - | - | - |
| R64 | 1 | Novak Djokovic | 139 |  Hugo Dellien | 6-2 6-2 | 3 | - | - | - | - | - | - | - |
| R32 | 69 | Kei Nishikori | 64 | Marcos Giron | 7-6(5) 3-6 6-1 | 3 | - | - | - | - | - | - | - |
| R32 | 57 | Dominik Koepfer | 190 | Max Purcell | 6-3 6-0 | 3 | - | - | - | - | - | - | - |
| R64 | 25 | Karen Khachanov | 55 | Yoshihito Nishioka | 3-6 6-1 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 24 | Aslan Karatsev | 54 | Tommy Paul | 6-3 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 66 | Ilya Ivashka | 18 | Gael Monfils | 6-4 4-6 7-5 | 3 | - | - | - | - | - | - | - |
| R32 | 31 | Fabio Fognini | 79 | Egor Gerasimov | 6-4 7-6(4) | 3 | - | - | - | - | - | - | - |
| R32 | 28 | Ugo Humbert | 50 | Miomir Kecmanovic | 4-6 7-6(5) 7-5 | 3 | - | - | - | - | - | - | - |
| R64 | 31 | Fabio Fognini | 114 | Yuichi Sugita | 6-4 6-3 | 3 | - | - | - | - | - | - | - |
| R64 | 44 | John Millman | 61 | Lorenzo Musetti | 6-3 6-4 | 3 | - | - | - | - | - | - | - |
| R64 | 53 | Frances Tiafoe | 71 |  Soonwoo Kwon | 6-3 6-2 | 3 | - | - | - | - | - | - | - |
| R64 | 48 | Jan-Lennard Struff | 95 | Thiago Monteiro | 6-3 6-4 | 3 | - | - | - | - | - | - | - |
| R32 | 25 | Karen Khachanov | 77 | James Duckworth | 7-5 6-1 | 3 | - | - | - | - | - | - | - |
| R32 | 68 | Jeremy Chardy | 24 | Aslan Karatsev | 7-5 4-6 6-3 | 3 | - | - | - | - | - | - | - |
| R32 | 13 | Diego Schwartzman | 145 | Tomas Machac | 6-4 7-5 | 3 | - | - | - | - | - | - | - |
| R32 | 142 | Liam Broady | 12 | Hubert Hurkacz | 7-5 3-6 6-3 | 3 | - | - | - | - | - | - | - |
| R32 | 11 | Pablo Carreno Busta | 36 | Marin Cilic | 5-7 6-4 6-4 | 3 | - | - | - | - | - | - | - |
| R32 | 5 | Alexander Zverev | 113 | Daniel Elahi Galan | 6-2 6-2 | 3 | - | - | - | - | - | - | - |
| R32 | 4 | Stefanos Tsitsipas | 53 | Frances Tiafoe | 6-3 6-4 | 3 | - | - | - | - | - | - | - |
| R32 | 2 | Daniil Medvedev | 160 | Sumit Nagal | 6-2 6-1 | 3 | - | - | - | - | - | - | - |
| R32 | 1 | Novak Djokovic | 48 | Jan-Lennard Struff | 6-4 6-3 | 3 | - | - | - | - | - | - | - |
| R16 | 69 | Kei Nishikori | 66 | Ilya Ivashka | 7-6(7) 6-0 | 3 | - | - | - | - | - | - | - |
| R16 | 68 | Jeremy Chardy | 142 | Liam Broady | 7-6(3) 4-6 6-1 | 3 | - | - | - | - | - | - | - |
| R16 | 25 | Karen Khachanov | 13 | Diego Schwartzman | 6-1 2-6 6-1 | 3 | - | - | - | - | - | - | - |
| R16 | 11 | Pablo Carreno Busta | 57 | Dominik Koepfer | 7-6(7) 6-3 | 3 | - | - | - | - | - | - | - |
| R16 | 5 | Alexander Zverev | 42 | Nikoloz Basilashvili | 6-4 7-6(5) | 3 | - | - | - | - | - | - | - |
| R16 | 28 | Ugo Humbert | 4 | Stefanos Tsitsipas | 2-6 7-6(4) 6-2 | 3 | - | - | - | - | - | - | - |
| R16 | 2 | Daniil Medvedev | 31 | Fabio Fognini | 6-2 3-6 6-2 | 3 | - | - | - | - | - | - | - |
| R16 | 1 | Novak Djokovic | 35 | Alejandro Davidovich Fokina | 6-3 6-1 | 3 | - | - | - | - | - | - | - |
| QF | 25 | Karen Khachanov | 28 | Ugo Humbert | 7-6(4) 4-6 6-3 | 3 | - | - | - | - | - | - | - |
| QF | 5 | Alexander Zverev | 68 | Jeremy Chardy | 6-4 6-1 | 3 | - | - | - | - | - | - | - |
| QF | 11 | Pablo Carreno Busta | 2 | Daniil Medvedev | 6-2 7-6(5) | 3 | - | - | - | - | - | - | - |
| QF | 1 | Novak Djokovic | 69 | Kei Nishikori | 6-2 6-0 | 3 | - | - | - | - | - | - | - |
| SF | 25 | Karen Khachanov | 11 | Pablo Carreno Busta | 6-3 6-3 | 3 | - | - | - | - | - | - | - |
| SF | 5 | Alexander Zverev | 1 | Novak Djokovic | 1-6 6-3 6-1 | 3 | - | - | - | - | - | - | - |
| BR | 11 | Pablo Carreno Busta | 1 | Novak Djokovic | 6-4 6-7(6) 6-3 | 3 | - | - | - | - | - | - | - |
| F | 5 | Alexander Zverev | 25 | Karen Khachanov | 6-3 6-1 | 3 | - | - | - | - | - | - | - |
