| 2021-11-01 | Paris Masters | Hard | R64 | 46 |  Ilya Ivashka | 44 |  Albert Ramos-Vinolas | 6-3 7-6(2) | H2H | 3 | 94 | 15 | 2 | 64.3% | 82.2% | 56.0% | 2/2 |
| 2021-10-25 | St. Petersburg | Hard | R32 | 35 |  Marin Cilic | 43 | Albert Ramos-Vinolas | 6-2 6-3 | H2H | 3 | 83 | 10 | 1 | 46.7% | 85.7% | 56.3% | 2/2 |
| 2021-10-18 | Antwerp | Hard | R32 | 50 |  Jan-Lennard Struff | 45 | Albert Ramos-Vinolas | 6-3 3-6 6-3 | H2H | 3 | 106 | 12 | 1 | 60.5% | 79.6% | 65.6% | 7/8 |
| 2021-10-04 | Indian Wells Masters | Hard | R32 | 36 |  Nikoloz Basilashvili (29) | 48 | Albert Ramos-Vinolas | 4-6 7-6(2) 6-2 | H2H | 3 | 143 | 8 | 8 | 54.1% | 73.6% | 42.2% | 6/10 |
| 2021-10-04 | Indian Wells Masters | Hard | R64 | 48 | Albert Ramos-Vinolas | 11 |  Felix Auger-Aliassime (7) | 6-4 6-2 | H2H | 3 | 76 | 0 | 3 | 64.4% | 82.8% | 56.3% | 1/2 |
| 2021-10-04 | Indian Wells Masters | Hard | R128 | 48 | Albert Ramos-Vinolas | 62 |  Lorenzo Musetti | 6-1 6-3 | H2H | 3 | 86 | 0 | 3 | 58.5% | 83.9% | 36.4% | 5/6 |
| 2021-08-30 | US Open | Hard | R64 | 4 | Alexander Zverev (4) | 48 | Albert Ramos-Vinolas | 6-1 6-0 6-3 | H2H | 5 | 74 | 11 | 3 | 81.1% | 93.0% | 40.0% | 0/0 |
| 2021-08-30 | US Open | Hard | R128 | 48 | Albert Ramos-Vinolas | 133 |  Lucas Pouille | 6-1 5-7 5-7 7-5 6-4 | H2H | 5 | 221 | 7 | 7 | 69.4% | 75.0% | 56.8% | 4/7 |
| 2021-08-23 | Winston-Salem | Hard | R32 | 90 |  Mikael Ymer | 48 | Albert Ramos-Vinolas (11) | 6-3 6-1 | H2H | 3 | 67 | 3 | 0 | 74.1% | 75.0% | 42.9% | 1/1 |
| 2021-08-16 | Cincinnati Masters | Hard | R64 | 49 | Albert Ramos-Vinolas | 41 |  Taylor Fritz | 4-6 6-4 6-4 | H2H | 3 | 135 | 8 | 3 | 60.3% | 76.6% | 54.8% | 3/6 |
