| R64 | 88 |  Andreas SeppiHard | 123 |  Yasutaka UchiyamaHard | 3-6 7-5 6-3 | 3 | 123 | 4 | 1 | 44.7% | 76.5% | 71.4% | 2/4 |
| R64 | 130 |  Jenson BrooksbyHard | 75 |  Kevin AndersonHard | 7-6(4) 6-3 | 3 | 109 | 1 | 5 | 60.0% | 80.4% | 50.0% | 2/2 |
| R64 | 168 |  Elias YmerHard | 62 |  Jordan ThompsonHard | 3-6 7-5 6-3 | 3 | 172 | 4 | 10 | 47.3% | 67.9% | 33.9% | 9/16 |
| R64 | 113 |  Daniel Elahi GalanHard | 55 | Tommy PaulHard | 6-4 6-3 | 3 | 85 | 3 | 1 | 68.4% | 79.5% | 61.1% | 1/1 |
| R64 | 81 | Steve JohnsonHard | 204 |  Ramkumar RamanathanHard | 6-3 7-6(0) | 3 | 84 | 11 | 1 | 61.1% | 77.3% | 57.1% | 1/2 |
| R64 | 86 |  Ricardas BerankisHard | 174 | Mitchell KruegerHard | 7-6(4) 6-2 | 3 | 93 | 2 | 1 | 64.7% | 81.8% | 58.3% | 2/2 |
| R64 | 61 |  Vasek PospisilHard | 165 |  Emilio GomezHard | 4-6 6-3 6-3 | 3 | 131 | 10 | 7 | 57.6% | 73.5% | 44.4% | 1/4 |
| R64 | 69 |  Emil RuusuvuoriHard | 158 | Prajnesh GunneswaranHard | 2-6 6-1 6-1 | 3 | 84 | 3 | 2 | 54.5% | 80.0% | 60.0% | 0/2 |
| R64 | 89 | Brandon NakashimaHard | 72 | Alexei PopyrinHard | 6-3 6-3 | 3 | 69 | 8 | 1 | 63.0% | 82.4% | 60.0% | 2/2 |
| R64 | 103 | Denis KudlaHard | 92 |  Feliciano LopezHard | 6-3 6-7(5) 6-3 | 3 | 140 | 12 | 4 | 52.7% | 72.4% | 67.3% | 6/6 |
| R64 | 107 | Mackenzie McDonaldHard | 77 | Nick KyrgiosHard | 6-4 6-4 | 3 | 77 | 7 | 1 | 57.1% | 80.6% | 59.3% | 5/5 |
| R64 | 65 |  Ilya IvashkaHard | 78 | Egor GerasimovHard | 7-5 6-4 | 3 | 105 | 6 | 4 | 55.4% | 80.5% | 48.5% | 3/4 |
| R64 | 64 | Marcos GironHard | 157 |  Illya MarchenkoHard | 4-6 6-4 7-6(1) | 3 | 179 | 10 | 4 | 53.3% | 73.7% | 50.0% | 9/14 |
| R64 | 67 | Kei NishikoriHard | 68 | Sam QuerreyHard | 6-4 6-3 | 3 | 85 | 2 | 2 | 73.0% | 76.1% | 58.8% | 5/5 |
| R64 | 83 | Tennys SandgrenHard | 80 | James DuckworthHard | 6-3 2-6 6-2 | 3 | 92 | 10 | 3 | 65.6% | 77.5% | 61.9% | 4/6 |
| R64 | 192 | Jack SockHard | 56 | Yoshihito NishiokaHard | 6-7(3) 4-0 RET | 3 | 97 | 3 | 4 | 51.5% | 68.6% | 39.4% | 3/5 |
| R32 | 15 | Felix Auger-AliassimeHard | 88 | Andreas SeppiHard | 2-6 6-2 6-2 | 3 | 119 | 9 | 2 | 54.9% | 76.9% | 43.8% | 3/6 |
| R32 | 130 | Jenson BrooksbyHard | 53 | Frances TiafoeHard | 7-6(4) 7-5 | 3 | 113 | 1 | 0 | 69.6% | 68.8% | 76.2% | 1/2 |
| R32 | 43 | John MillmanHard | 168 | Elias YmerHard | 6-2 7-6(8) | 3 | 121 | 3 | 0 | 56.0% | 70.2% | 43.2% | 9/12 |
| R32 | 36 | Reilly OpelkaHard | 113 | Daniel Elahi GalanHard | 7-6(1) 6-3 | 3 | 95 | 9 | 2 | 58.1% | 83.7% | 61.3% | 5/5 |
| R32 | 81 | Steve JohnsonHard | 18 | Alex de MinaurHard | 6-7(5) 6-4 6-2 | 3 | 137 | 7 | 4 | 55.8% | 73.6% | 61.9% | 2/3 |
| R32 | 86 | Ricardas BerankisHard | 59 |  Miomir KecmanovicHard | 6-3 6-2 | 3 | 85 | 3 | 2 | 53.3% | 78.1% | 53.6% | 3/4 |
| R32 | 45 | Sebastian KordaHard | 61 | Vasek PospisilHard | 7-5 6-4 | 3 | 88 | 11 | 1 | 59.3% | 80.0% | 75.0% | 3/3 |
| R32 | 24 | Jannik SinnerHard | 69 | Emil RuusuvuoriHard | 6-2 6-4 | 3 | 78 | 3 | 0 | 40.8% | 85.0% | 69.0% | 0/0 |
| R32 | 89 | Brandon NakashimaHard | 27 |  Daniel EvansHard | 7-6(1) 6-0 | 3 | 88 | 5 | 0 | 56.9% | 78.8% | 60.0% | 2/3 |
| R32 | 103 | Denis KudlaHard | 42 | Taylor FritzHard | 6-4 6-2 | 3 | 79 | 5 | 3 | 64.5% | 75.0% | 36.4% | 7/9 |
| R32 | 107 | Mackenzie McDonaldHard | 49 |  Benoit PaireHard | 6-7(6) 6-4 6-4 | 3 | 137 | 5 | 1 | 59.0% | 69.6% | 47.9% | 9/12 |
| R32 | 65 | Ilya IvashkaHard | 21 |  Grigor DimitrovHard | 6-2 7-6(4) | 3 | 111 | 5 | 3 | 52.8% | 81.6% | 55.9% | 1/2 |
| R32 | 29 | Cameron NorrieHard | 64 | Marcos GironHard | 6-4 6-3 | 3 | 87 | 4 | 2 | 67.9% | 69.4% | 58.8% | 4/7 |
| R32 | 67 | Kei NishikoriHard | 39 |  Alexander BublikHard | 6-2 7-5 | 3 | 96 | 3 | 3 | 60.9% | 57.1% | 70.4% | 6/8 |
| R32 | 50 | Lloyd HarrisHard | 83 | Tennys SandgrenHard | 6-4 1-0 RET | 3 | 51 | 10 | 0 | 75.9% | 72.7% | 71.4% | 3/3 |
| R32 | 3 | Rafael NadalHard | 192 | Jack SockHard | 6-2 4-6 7-6(1) | 3 | 184 | 8 | 3 | 58.8% | 70.1% | 57.4% | 8/10 |
| R16 | 130 | Jenson BrooksbyHard | 15 | Felix Auger-AliassimeHard | 6-3 6-4 | 3 | 85 | 1 | 1 | 60.4% | 81.3% | 76.2% | 2/2 |
| R16 | 43 | John MillmanHard | 36 | Reilly OpelkaHard | 6-3 7-6(4) | 3 | 94 | 4 | 1 | 56.3% | 72.5% | 64.5% | 1/2 |
| R16 | 81 | Steve JohnsonHard | 86 | Ricardas BerankisHard | 6-2 6-1 | 3 | 63 | 7 | 1 | 52.7% | 69.0% | 69.2% | 3/3 |
| R16 | 24 | Jannik SinnerHard | 45 | Sebastian KordaHard | 7-6(3) 7-6(3) | 3 | 116 | 3 | 5 | 51.8% | 72.1% | 55.0% | 2/5 |
| R16 | 103 | Denis KudlaHard | 89 | Brandon NakashimaHard | 3-6 7-6(3) 6-4 | 3 | 136 | 7 | 6 | 57.1% | 75.0% | 47.6% | 3/6 |
| R16 | 107 | Mackenzie McDonaldHard | 65 | Ilya IvashkaHard | 6-4 6-4 | 3 | 83 | 8 | 0 | 63.3% | 81.6% | 54.5% | 3/4 |
| R16 | 67 | Kei NishikoriHard | 29 | Cameron NorrieHard | 3-6 6-3 6-3 | 3 | 129 | 5 | 2 | 68.4% | 61.5% | 66.7% | 2/6 |
| R16 | 50 | Lloyd HarrisHard | 3 | Rafael NadalHard | 6-4 1-6 6-4 | 3 | 130 | 16 | 3 | 63.0% | 76.5% | 43.3% | 4/6 |
| QF | 130 | Jenson BrooksbyHard | 43 | John MillmanHard | 6-1 6-2 | 3 | 67 | 3 | 0 | 55.8% | 87.5% | 57.9% | 1/1 |
| QF | 24 | Jannik SinnerHard | 81 | Steve JohnsonHard | 6-4 6-2 | 3 | 71 | 7 | 1 | 56.9% | 93.1% | 54.5% | 3/3 |
| QF | 107 | Mackenzie McDonaldHard | 103 | Denis KudlaHard | 6-3 6-2 | 3 | 75 | 6 | 2 | 60.8% | 80.6% | 60.0% | 1/1 |
| QF | 67 | Kei NishikoriHard | 50 | Lloyd HarrisHard | 6-3 7-5 | 3 | 113 | 1 | 1 | 62.5% | 70.0% | 58.3% | 5/6 |
| SF | 24 | Jannik SinnerHard | 130 | Jenson BrooksbyHard | 7-6(2) 6-1 | 3 | 89 | 6 | 1 | 52.6% | 83.3% | 70.4% | 3/3 |
| SF | 107 | Mackenzie McDonaldHard | 67 | Kei NishikoriHard | 6-4 3-6 7-5 | 3 | 165 | 4 | 3 | 60.7% | 63.1% | 47.6% | 8/12 |
| F | 24 | Jannik SinnerHard | 107 | Mackenzie McDonaldHard | 7-5 4-6 7-5 | 3 | 172 | - | - | - | - | - | - |
