| R32 | 100 |  Francisco CerundoloClay | 52 |  Benoit PaireClay | 6-3 4-6 6-2 | 3 | 128 | 3 | 5 | 59.7% | 67.4% | 51.6% | 4/7 |
| R32 | 70 |  Miomir KecmanovicClay | 224 |  Felipe Meligeni AlvesClay | 6-3 6-0 | 3 | 64 | 0 | 0 | 58.1% | 68.0% | 61.1% | 2/4 |
| R32 | 21 |  Lorenzo SonegoClay | 56 | Laslo DjereClay | 6-2 6-0 | 3 | 69 | 3 | 0 | 66.7% | 84.6% | 53.8% | 1/1 |
| R32 | 62 |  Pedro MartinezClay | 663 |  Juncheng ShangClay | 6-3 6-4 | 3 | 102 | 2 | 4 | 65.3% | 74.5% | 60.0% | 3/3 |
| R32 | 74 | Pablo AndujarClay | 104 |  Pablo CuevasClay | 7-6(2) 7-5 | 3 | - | 4 | 0 | 100.0% | 100.0% | NaN% | 0/0 |
| R32 | 33 | Albert Ramos-VinolasClay | 144 | Juan Ignacio LonderoClay | 6-3 6-4 | 3 | 86 | 7 | 2 | 67.9% | 69.4% | 52.9% | 0/1 |
| R32 | 63 | Federico CoriaClay | 19 |  Cristian GarinClay | 6-2 6-0 | 3 | 76 | 4 | 0 | 57.9% | 81.8% | 68.8% | 2/2 |
| R32 | 172 | Fernando VerdascoClay | 39 | Dusan LajovicClay | 7-6(4) 6-3 | 3 | 113 | 4 | 1 | 66.7% | 66.7% | 59.3% | 7/9 |
| R32 | 38 | Fabio FogniniClay | 77 | Facundo BagnisClay | 6-2 6-4 | 3 | 73 | 4 | 1 | 74.0% | 83.8% | 53.8% | 2/2 |
| R32 | 29 | Carlos AlcarazClay | 89 | Jaume MunarClay | 2-6 6-2 6-1 | 3 | 135 | 2 | 3 | 63.1% | 62.3% | 54.8% | 10/13 |
| R32 | 37 | Federico DelbonisClay | 112 |  Daniel Elahi GalanClay | 3-6 6-3 6-2 | 3 | 113 | 4 | 1 | 62.5% | 71.1% | 63.0% | 2/4 |
| R32 | 106 | Thiago MonteiroClay | 72 | Sebastian BaezClay | 1-6 6-4 6-4 | 3 | 145 | 3 | 1 | 72.4% | 61.9% | 50.0% | 2/6 |
| R16 | 100 | Francisco CerundoloClay | 78 | Roberto Carballes BaenaClay | 6-3 6-2 | 3 | 80 | 2 | 2 | 62.0% | 87.1% | 52.6% | 0/1 |
| R16 | 70 | Miomir KecmanovicClay | 21 | Lorenzo SonegoClay | 7-5 6-4 | 3 | 101 | 1 | 0 | 66.7% | 71.1% | 78.9% | 0/1 |
| R16 | 14 | Diego SchwartzmanClay | 62 | Pedro MartinezClay | 6-1 6-1 | 3 | 93 | 0 | 1 | 76.5% | 64.1% | 75.0% | 1/1 |
| R16 | 74 | Pablo AndujarClay | 33 | Albert Ramos-VinolasClay | 7-5 5-7 6-3 | 3 | 192 | 2 | 4 | 73.3% | 54.1% | 44.4% | 3/10 |
| R16 | 63 | Federico CoriaClay | 172 | Fernando VerdascoClay | 7-6(2) 4-6 6-4 | 3 | 181 | 3 | 3 | 66.9% | 62.0% | 59.0% | 13/17 |
| R16 | 38 | Fabio FogniniClay | 18 | Pablo Carreno BustaClay | 5-7 6-4 6-3 | 3 | 180 | 4 | 4 | 60.3% | 57.1% | 63.0% | 9/12 |
| R16 | 29 | Carlos AlcarazClay | 37 | Federico DelbonisClay | 6-4 7-6(1) | 3 | 109 | 2 | 3 | 63.6% | 69.0% | 62.5% | 0/2 |
| R16 | 6 | Matteo BerrettiniClay | 106 | Thiago MonteiroClay | 6-4 6-7(6) 6-3 | 3 | 171 | 14 | 2 | 78.6% | 79.0% | 40.9% | 2/3 |
| QF | 100 | Francisco CerundoloClay | 70 | Miomir KecmanovicClay | 5-7 6-2 6-4 | 3 | 137 | 7 | 7 | 50.0% | 71.7% | 52.8% | 9/12 |
| QF | 14 | Diego SchwartzmanClay | 74 | Pablo AndujarClay | 7-6(3) 4-6 6-4 | 3 | 213 | 2 | 2 | 60.0% | 55.1% | 52.2% | 12/19 |
| QF | 38 | Fabio FogniniClay | 63 | Federico CoriaClay | 6-4 6-2 | 3 | 77 | 1 | 2 | 66.7% | 76.5% | 70.6% | 2/3 |
| QF | 29 | Carlos AlcarazClay | 6 | Matteo BerrettiniClay | 6-2 2-6 6-2 | 3 | 122 | 1 | 4 | 62.1% | 73.2% | 56.0% | 0/2 |
| SF | 14 | Diego SchwartzmanClay | 100 | Francisco CerundoloClay | 7-6(4) 6-3 | 3 | 122 | 1 | 1 | 65.0% | 65.4% | 53.6% | 7/9 |
| SF | 29 | Carlos AlcarazClay | 38 | Fabio FogniniClay | 6-2 7-5 | 3 | 105 | 0 | 3 | 68.4% | 67.3% | 54.2% | 5/6 |
| F | 29 | Carlos AlcarazClay | 14 | Diego SchwartzmanClay | 6-4 6-2 | 3 | 86 | 1 | 0 | 68.0% | 76.5% | 37.5% | 2/4 |
