| R16 | 1 |  Novak DjokovicClay | 78 |  Andy MurrayClay | W/O | 3 | 0 | - | - | - | - | - | - |
| R64 | 24 |  Marin CilicClay | 43 |  Albert Ramos-VinolasClay | 6-3 3-6 6-4 | 3 | 134 | 18 | 3 | 60.4% | 75.9% | 44.7% | 7/10 |
| R64 | 63 |  Lorenzo MusettiClay | 48 |  Ilya IvashkaClay | 2-6 6-3 7-5 | 3 | 126 | 2 | 2 | 71.9% | 63.8% | 51.9% | 5/9 |
| R64 | 30 |  Sebastian KordaClay | 17 | Reilly OpelkaClay | 6-3 7-5 | 3 | 101 | 2 | 2 | 72.6% | 77.8% | 41.2% | 2/3 |
| R64 | 12 | Jannik SinnerClay | 35 | Tommy PaulClay | 6-7(4) 7-6(4) 6-3 | 3 | 180 | 8 | 3 | 59.3% | 71.9% | 65.9% | 2/4 |
| R64 | 22 |  Alex de MinaurClay | 44 | Pedro MartinezClay | 7-6(2) 1-6 6-3 | 3 | 164 | 6 | 1 | 56.3% | 65.5% | 42.2% | 12/17 |
| R64 | 39 |  Cristian GarinClay | 25 | Frances TiafoeClay | 6-1 6-3 | 3 | 60 | 6 | 0 | 60.9% | 85.7% | 38.9% | 0/1 |
| R64 | 174 |  Lucas PouilleClay | 26 |  Karen KhachanovClay | 6-3 6-4 | 3 | 95 | 1 | 1 | 63.5% | 66.0% | 66.7% | 7/7 |
| R64 | 20 |  Grigor DimitrovClay | 64 | Maxime CressyClay | 6-2 7-6(4) | 3 | 84 | 5 | 3 | 70.4% | 86.8% | 62.5% | 1/2 |
| R64 | 15 |  Diego SchwartzmanClay | 62 | Benoit PaireClay | 6-2 6-7(5) 6-1 | 3 | 126 | 2 | 0 | 66.3% | 78.2% | 75.0% | 2/2 |
| R64 | 19 | Roberto Bautista AgutClay | 42 | Jenson BrooksbyClay | 6-0 6-2 | 3 | 82 | 4 | 1 | 62.3% | 66.7% | 55.0% | 5/6 |
| R64 | 36 | Daniel EvansClay | 37 | Federico DelbonisClay | 6-3 6-4 | 3 | 96 | 6 | 1 | 75.4% | 76.1% | 40.0% | 1/2 |
| R64 | 121 | Jack DraperClay | 28 | Lorenzo SonegoClay | 6-4 6-3 | 3 | 98 | 4 | 0 | 50.8% | 78.1% | 54.8% | 3/4 |
| R64 | 27 |  Nikoloz BasilashviliClay | 51 | Fabio FogniniClay | 7-5 6-4 | 3 | 79 | 3 | 0 | 66.0% | 74.3% | 50.0% | 1/4 |
| R64 | 23 | John IsnerClay | 56 | Filip KrajinovicClay | 7-6(8) 6-4 | 3 | 97 | 30 | 2 | 67.1% | 78.4% | 56.0% | 1/2 |
| R64 | 11 | Cameron NorrieClay | 73 |  Soonwoo KwonClay | 7-5 7-5 | 3 | 109 | 9 | 0 | 74.6% | 72.0% | 41.2% | 2/4 |
| R64 | 31 |  Botic van de ZandschulpClay | 18 | Pablo Carreno BustaClay | 6-7(6) 7-6(1) 6-3 | 3 | 162 | 11 | 0 | 70.7% | 74.7% | 55.6% | 10/11 |
| R64 | 60 |  David GoffinClay | 34 | Aslan KaratsevClay | 6-2 7-5 | 3 | 91 | 9 | 2 | 66.1% | 75.6% | 61.9% | 3/4 |
| R64 | 32 | Miomir KecmanovicClay | 33 |  Alexander BublikClay | 6-4 7-5 | 3 | 76 | 0 | 0 | 58.5% | 83.9% | 81.8% | 0/0 |
| R64 | 77 | Dusan LajovicClay | 264 | Borna CoricClay | 6-3 4-6 6-4 | 3 | 140 | 7 | 3 | 70.7% | 78.5% | 48.1% | 5/6 |
| R64 | 29 | Alejandro Davidovich FokinaClay | 38 |  Lloyd HarrisClay | 7-5 6-3 | 3 | 78 | 2 | 3 | 61.0% | 88.9% | 65.2% | 1/1 |
| R64 | 14 |  Hubert HurkaczClay | 81 |  Hugo DellienClay | 7-5 6-7(11) 6-3 | 3 | 175 | 14 | 1 | 63.0% | 73.0% | 54.1% | 1/4 |
| R64 | 16 |  Denis ShapovalovClay | 46 | Ugo HumbertClay | 7-6(1) 6-3 | 3 | 116 | 5 | 1 | 69.7% | 66.1% | 70.4% | 9/9 |
| R64 | 78 | Andy MurrayClay | 91 |  Dominic ThiemClay | 6-3 6-4 | 3 | 102 | 9 | 2 | 58.1% | 77.8% | 69.2% | 3/3 |
| R64 | 21 | Gael MonfilsClay | 369 | Carlos Gimeno ValeroClay | 6-3 6-0 | 3 | 55 | 4 | 0 | 68.4% | 92.3% | 66.7% | 0/0 |
| R32 | 3 |  Alexander ZverevClay | 24 | Marin CilicClay | 4-6 6-4 6-4 | 3 | 137 | 11 | 4 | 77.5% | 76.8% | 45.0% | 6/8 |
| R32 | 63 | Lorenzo MusettiClay | 30 | Sebastian KordaClay | 6-4 6-3 | 3 | 101 | 1 | 3 | 61.7% | 70.3% | 47.8% | 4/6 |
| R32 | 12 | Jannik SinnerClay | 22 | Alex de MinaurClay | 6-4 6-1 | 3 | 74 | 1 | 3 | 60.0% | 70.0% | 55.0% | 2/4 |
| R32 | 10 | Felix Auger-AliassimeClay | 39 | Cristian GarinClay | 6-3 6-0 | 3 | 69 | 8 | 0 | 80.8% | 64.3% | 70.0% | 3/4 |
| R32 | 5 |  Stefanos TsitsipasClay | 174 | Lucas PouilleClay | 6-3 6-4 | 3 | 68 | 7 | 1 | 68.8% | 93.9% | 33.3% | 0/1 |
| R32 | 20 | Grigor DimitrovClay | 15 | Diego SchwartzmanClay | 6-0 6-3 | 3 | 69 | 6 | 1 | 72.5% | 82.8% | 54.5% | 1/1 |
| R32 | 36 | Daniel EvansClay | 19 | Roberto Bautista AgutClay | 6-3 5-7 7-6(2) | 3 | 178 | 9 | 1 | 74.2% | 82.6% | 37.5% | 6/8 |
| R32 | 8 | Andrey RublevClay | 121 | Jack DraperClay | 2-6 6-4 7-5 | 3 | 139 | 15 | 2 | 60.2% | 77.4% | 45.7% | 8/12 |
| R32 | 9 | Carlos AlcarazClay | 27 | Nikoloz BasilashviliClay | 6-3 7-5 | 3 | 83 | 4 | 1 | 64.8% | 65.7% | 57.9% | 2/5 |
| R32 | 11 | Cameron NorrieClay | 23 | John IsnerClay | 6-4 6-7(5) 6-4 | 3 | 135 | 8 | 1 | 75.6% | 77.9% | 68.2% | 0/1 |
| R32 | 60 | David GoffinClay | 31 | Botic van de ZandschulpClay | 6-4 6-2 | 3 | 90 | 2 | 3 | 55.4% | 69.4% | 62.1% | 4/5 |
| R32 | 4 | Rafael NadalClay | 32 | Miomir KecmanovicClay | 6-1 7-6(4) | 3 | 115 | 3 | 3 | 67.7% | 72.7% | 52.4% | 2/4 |
| R32 | 77 | Dusan LajovicClay | 7 |  Casper RuudClay | 7-6(7) 2-6 6-4 | 3 | 137 | 5 | 0 | 71.6% | 79.4% | 48.0% | 2/5 |
| R32 | 14 | Hubert HurkaczClay | 29 | Alejandro Davidovich FokinaClay | 6-4 4-6 7-6(5) | 3 | 147 | 13 | 2 | 71.4% | 65.3% | 66.7% | 6/9 |
| R32 | 78 | Andy MurrayClay | 16 | Denis ShapovalovClay | 6-1 3-6 6-2 | 3 | 128 | 3 | 0 | 65.2% | 77.8% | 54.2% | 2/3 |
| R32 | 1 | Novak DjokovicClay | 21 | Gael MonfilsClay | 6-3 6-2 | 3 | 87 | 2 | 3 | 63.2% | 69.8% | 56.0% | 5/5 |
| R16 | 3 | Alexander ZverevClay | 63 | Lorenzo MusettiClay | 6-3 1-0 RET | 3 | 39 | 7 | 0 | 78.3% | 88.9% | 80.0% | 0/0 |
| R16 | 10 | Felix Auger-AliassimeClay | 12 | Jannik SinnerClay | 6-1 6-2 | 3 | 79 | 5 | 0 | 70.7% | 89.7% | 58.3% | 0/0 |
| R16 | 5 | Stefanos TsitsipasClay | 20 | Grigor DimitrovClay | 6-3 6-4 | 3 | 78 | 10 | 0 | 69.4% | 85.3% | 80.0% | 0/0 |
| R16 | 8 | Andrey RublevClay | 36 | Daniel EvansClay | 7-6(7) 7-5 | 3 | 148 | 8 | 5 | 51.6% | 87.2% | 36.4% | 3/5 |
| R16 | 9 | Carlos AlcarazClay | 11 | Cameron NorrieClay | 6-4 6-7(4) 6-3 | 3 | 159 | 7 | 4 | 69.5% | 71.2% | 43.8% | 7/9 |
| R16 | 4 | Rafael NadalClay | 60 | David GoffinClay | 6-3 5-7 7-6(9) | 3 | 189 | 7 | 4 | 66.1% | 76.4% | 54.1% | 2/5 |
| R16 | 14 | Hubert HurkaczClay | 77 | Dusan LajovicClay | 7-5 6-3 | 3 | 96 | 16 | 1 | 58.3% | 83.3% | 50.0% | 3/3 |
| QF | 3 | Alexander ZverevClay | 10 | Felix Auger-AliassimeClay | 6-3 7-5 | 3 | 115 | 1 | 9 | 63.2% | 74.4% | 56.0% | 3/4 |
| QF | 5 | Stefanos TsitsipasClay | 8 | Andrey RublevClay | 6-3 2-6 6-4 | 3 | 119 | 10 | 1 | 64.0% | 81.3% | 51.9% | 3/5 |
| QF | 9 | Carlos AlcarazClay | 4 | Rafael NadalClay | 6-2 1-6 6-3 | 3 | 148 | 4 | 3 | 55.7% | 66.7% | 51.6% | 6/9 |
| QF | 1 | Novak DjokovicClay | 14 | Hubert HurkaczClay | 6-3 6-4 | 3 | 81 | 6 | 1 | 65.5% | 80.6% | 68.4% | 0/0 |
| SF | 3 | Alexander ZverevClay | 5 | Stefanos TsitsipasClay | 6-4 3-6 6-2 | 3 | 113 | 4 | 4 | 72.7% | 83.3% | 55.6% | 1/2 |
| SF | 9 | Carlos AlcarazClay | 1 | Novak DjokovicClay | 6-7(5) 7-5 7-6(5) | 3 | 215 | 4 | 4 | 66.9% | 73.6% | 51.1% | 5/6 |
| F | 9 | Carlos AlcarazClay | 3 | Alexander ZverevClay | 6-3 6-1 | 3 | 62 | 1 | 0 | 71.1% | 88.9% | 72.7% | 0/0 |
