| R32 | 4 |  Juan Martin del PotroHard | 72 |  Yoshihito NishiokaHard | 6-3 7-5 | 3 | 110 | 12 | 4 | 58.3% | 71.4% | 56.7% | 3/4 |
| R32 | 56 |  Reilly OpelkaHard | 79 | Tennys SandgrenHard | 6-4 6-0 | 3 | 55 | 8 | 2 | 58.3% | 89.3% | 55.0% | 1/1 |
| R32 | 101 |  Guillermo Garcia-LopezHard | 120 | Jared DonaldsonHard | 2-6 6-3 6-3 | 3 | 132 | 7 | 5 | 56.7% | 62.7% | 43.6% | 8/13 |
| R32 | 84 | Mackenzie McDonaldHard | 42 | Taylor FritzHard | 3-6 6-4 6-3 | 3 | 95 | 5 | 2 | 61.5% | 81.3% | 53.3% | 1/2 |
| R32 | 34 | Steve JohnsonHard | 131 |  Jason JungHard | 7-6(3) 6-4 | 3 | 111 | 12 | 4 | 64.3% | 72.2% | 43.3% | 7/9 |
| R32 | 105 |  Paolo LorenziHard | 189 | Tim SmyczekHard | 7-5 6-3 | 3 | 90 | 2 | 2 | 55.9% | 78.9% | 66.7% | 1/1 |
| R32 | 82 |  Radu AlbotHard | 88 |  Ivo KarlovicHard | 7-6(2) 6-4 | 3 | 97 | 3 | 4 | 62.4% | 75.5% | 56.3% | 4/4 |
| R32 | 64 |  Nick KyrgiosHard | 37 | John MillmanHard | 6-4 6-7(1) 7-6(3) | 3 | 124 | 19 | 11 | 58.6% | 84.6% | 50.0% | 1/1 |
| R32 | 52 | Andreas SeppiHard | 85 | Bernard TomicHard | 6-4 7-5 | 3 | 76 | 5 | 3 | 50.7% | 81.6% | 54.1% | 6/6 |
| R32 | 68 | Jordan ThompsonHard | 111 | Marcel GranollersHard | 7-5 6-1 | 3 | 81 | 6 | 1 | 54.2% | 84.4% | 51.9% | 4/5 |
| R32 | 98 |  Lloyd HarrisHard | 162 |  Darian KingHard | 7-6(1) 6-3 | 3 | 96 | 10 | 4 | 62.1% | 74.1% | 45.5% | 14/16 |
| R32 | 148 |  Daniel EvansHard | 29 | Frances TiafoeHard | 3-6 7-6(1) 7-5 | 3 | 136 | 4 | 4 | 64.0% | 75.4% | 40.6% | 3/8 |
| R32 | 51 |  Adrian MannarinoHard | 107 |  Brayden SchnurHard | 6-2 6-2 | 3 | 52 | 2 | 0 | 64.1% | 80.0% | 92.9% | 2/2 |
| R32 | 102 |  Denis IstominHard | 67 | Feliciano LopezHard | 7-6(5) 6-2 | 3 | 99 | 5 | 1 | 59.7% | 80.0% | 51.9% | 1/2 |
| R32 | 133 |  Lukas LackoHard | 181 | Yosuke WatanukiHard | 6-4 6-4 | 3 | 93 | 7 | 1 | 57.4% | 82.1% | 55.2% | 4/4 |
| R32 | 9 | John IsnerHard | 122 | Peter PolanskyHard | 6-3 7-6(4) | 3 | 92 | 23 | 5 | 61.8% | 87.2% | 48.3% | 4/4 |
| R16 | 4 | Juan Martin del PotroHard | 56 | Reilly OpelkaHard | 6-4 6-4 | 3 | 73 | 5 | 0 | 77.6% | 75.6% | 69.2% | 0/0 |
| R16 | 84 | Mackenzie McDonaldHard | 101 | Guillermo Garcia-LopezHard | 7-5 6-4 | 3 | 89 | 5 | 1 | 66.7% | 78.6% | 66.7% | 2/2 |
| R16 | 34 | Steve JohnsonHard | 105 | Paolo LorenziHard | 7-5 7-5 | 3 | 117 | 7 | 2 | 52.2% | 86.1% | 66.7% | 2/2 |
| R16 | 82 | Radu AlbotHard | 64 | Nick KyrgiosHard | 6-2 3-6 6-3 | 3 | 84 | 6 | 1 | 64.5% | 75.5% | 66.7% | 5/6 |
| R16 | 52 | Andreas SeppiHard | 68 | Jordan ThompsonHard | 6-3 4-6 6-1 | 3 | 104 | 7 | 4 | 59.0% | 86.1% | 56.0% | 0/2 |
| R16 | 148 | Daniel EvansHard | 98 | Lloyd HarrisHard | 6-0 6-2 | 3 | 68 | 0 | 2 | 67.5% | 74.1% | 53.8% | 1/2 |
| R16 | 51 | Adrian MannarinoHard | 102 | Denis IstominHard | 6-2 7-6(3) | 3 | 78 | 5 | 0 | 63.5% | 78.8% | 73.7% | 0/1 |
| R16 | 9 | John IsnerHard | 133 | Lukas LackoHard | 6-4 6-3 | 3 | 70 | 18 | 0 | 74.4% | 96.9% | 54.5% | 2/2 |
| QF | 84 | Mackenzie McDonaldHard | 4 | Juan Martin del PotroHard | 6-4 3-6 7-6(5) | 3 | 138 | 9 | 4 | 51.6% | 81.6% | 58.7% | 2/3 |
| QF | 82 | Radu AlbotHard | 34 | Steve JohnsonHard | 1-6 6-3 7-6(5) | 3 | 127 | 5 | 4 | 67.0% | 71.2% | 55.2% | 2/5 |
| QF | 148 | Daniel EvansHard | 52 | Andreas SeppiHard | 6-4 6-4 | 3 | 87 | 3 | 3 | 67.7% | 72.7% | 57.1% | 2/3 |
| QF | 9 | John IsnerHard | 51 | Adrian MannarinoHard | 7-6(2) 6-4 | 3 | 93 | 24 | 1 | 77.1% | 77.8% | 68.8% | 3/3 |
| SF | 82 | Radu AlbotHard | 84 | Mackenzie McDonaldHard | 3-6 6-0 6-0 | 3 | 90 | 6 | 2 | 59.6% | 71.0% | 57.1% | 2/4 |
| SF | 148 | Daniel EvansHard | 9 | John IsnerHard | 3-6 6-2 6-3 | 3 | 92 | 4 | 0 | 68.9% | 88.1% | 68.4% | 0/1 |
| F | 82 | Radu AlbotHard | 148 | Daniel EvansHard | 3-6 6-3 7-6(7) | 3 | 171 | 1 | 5 | 59.0% | 62.7% | 63.4% | 6/9 |
