| R64 | 45 |  Sam QuerreyHard | 41 |  Pierre-Hugues HerbertHard | 7-6(2) 7-6(1) | 3 | 97 | 18 | 7 | 52.5% | 90.5% | 42.1% | 3/5 |
| R64 | 53 |  Pablo Carreno BustaHard | 35 | Gilles SimonHard | 7-5 7-6(4) | 3 | 137 | 4 | 2 | 67.0% | 68.3% | 58.1% | 5/6 |
| R64 | 16 | John IsnerHard | 28 |  Dusan LajovicHard | 7-6(3) 1-6 7-5 | 3 | 136 | 27 | 1 | 72.5% | 79.7% | 35.7% | 8/10 |
| R64 | 34 |  Denis ShapovalovHard | 43 |  Joao SousaHard | 2-6 6-3 6-2 | 3 | 98 | 5 | 6 | 56.2% | 75.6% | 59.4% | 4/6 |
| R64 | 31 | Lucas PouilleHard | 111 | Denis KudlaHard | 6-3 7-6(6) | 3 | 98 | 8 | 2 | 61.5% | 58.3% | 60.0% | 4/7 |
| R64 | 27 |  Nick KyrgiosHard | 47 |  Lorenzo SonegoHard | 7-5 6-4 | 3 | 79 | 4 | 1 | 57.4% | 93.5% | 73.9% | 0/0 |
| R64 | 55 |  Juan Ignacio LonderoHard | 26 | Matteo BerrettiniHard | 7-6(3) 6-3 | 3 | 87 | 5 | 1 | 68.3% | 81.4% | 70.0% | 0/1 |
| R64 | 23 |  Stan WawrinkaHard | 74 |  Grigor DimitrovHard | 5-7 6-4 7-6(4) | 3 | 155 | 10 | 0 | 50.9% | 72.7% | 58.5% | 4/8 |
| R64 | 70 |  Andrey RublevHard | 17 |  Nikoloz BasilashviliHard | 6-7(4) 6-4 6-2 | 3 | 117 | 16 | 3 | 57.6% | 84.9% | 53.8% | 1/1 |
| R64 | 8 | Daniil MedvedevHard | 30 |  Kyle EdmundHard | 6-2 7-5 | 3 | 78 | 8 | 2 | 66.7% | 67.6% | 76.5% | 0/2 |
| R64 | 29 | Benoit PaireHard | 33 | Fernando VerdascoHard | 6-4 RET | 3 | 48 | 4 | 3 | 60.0% | 88.9% | 58.3% | 0/0 |
| R64 | 36 |  Jan-Lennard StruffHard | 80 |  Ivo KarlovicHard | 7-5 7-6(4) | 3 | 91 | 12 | 2 | 46.6% | 79.4% | 74.4% | 0/0 |
| R64 | 58 | Miomir KecmanovicHard | 21 | Felix Auger-AliassimeHard | 6-3 6-3 | 3 | 63 | 4 | 1 | 60.4% | 89.7% | 57.9% | 0/0 |
| R64 | 52 | Frances TiafoeHard | 15 | Gael MonfilsHard | 7-6(7) 6-3 | 3 | 90 | 3 | 1 | 56.3% | 75.0% | 64.5% | 2/3 |
| R64 | 11 | Roberto Bautista AgutHard | 40 |  Hubert HurkaczHard | 7-6(6) 6-3 | 3 | 97 | 3 | 3 | 59.7% | 70.3% | 64.0% | 3/4 |
| R64 | 39 |  Radu AlbotHard | 18 | Marin CilicHard | 6-4 7-6(6) | 3 | 114 | 6 | 5 | 55.3% | 74.5% | 57.9% | 6/6 |
| R64 | 24 | Diego SchwartzmanHard | 37 | Laslo DjereHard | 7-6(2) 6-3 | 3 | 106 | 0 | 5 | 58.1% | 67.4% | 48.4% | 5/8 |
| R64 | 56 | Richard GasquetHard | 324 | Andy MurrayHard | 6-4 6-4 | 3 | 96 | 4 | 6 | 60.3% | 80.5% | 48.1% | 4/5 |
| R64 | 77 |  Yoshihito NishiokaHard | 49 | Jordan ThompsonHard | 7-5 5-7 6-4 | 3 | 143 | 1 | 0 | 64.4% | 67.7% | 58.3% | 8/12 |
| R64 | 38 | Alex de MinaurHard | 65 | Marco CecchinatoHard | 6-7(5) 6-1 6-2 | 3 | 131 | 6 | 4 | 54.8% | 74.5% | 66.7% | 0/0 |
| R64 | 42 | Reilly OpelkaHard | 13 | Borna CoricHard | 4-6 6-3 7-5 | 3 | 138 | 27 | 3 | 62.6% | 77.6% | 55.0% | 10/11 |
| R64 | 19 |  David GoffinHard | 25 | Taylor FritzHard | 6-4 4-6 6-4 | 3 | 145 | 6 | 9 | 58.2% | 64.1% | 52.2% | 8/11 |
| R64 | 22 | Guido PellaHard | 54 |  Casper RuudHard | 7-5 7-6(4) | 3 | 114 | 8 | 4 | 72.7% | 68.8% | 58.3% | 9/11 |
| R64 | 59 | Adrian MannarinoHard | 32 |  Cristian GarinHard | 6-4 6-1 | 3 | 70 | 5 | 1 | 48.1% | 76.0% | 63.0% | 1/2 |
| R32 | 1 | Novak DjokovicHard | 45 | Sam QuerreyHard | 7-5 6-1 | 3 | 78 | 15 | 5 | 58.7% | 83.8% | 50.0% | 4/5 |
| R32 | 53 | Pablo Carreno BustaHard | 16 | John IsnerHard | 6-4 6-7(1) 7-6(6) | 3 | 153 | 1 | 1 | 73.6% | 78.2% | 64.3% | 6/6 |
| R32 | 31 | Lucas PouilleHard | 34 | Denis ShapovalovHard | 6-4 6-4 | 3 | 79 | 0 | 3 | 50.0% | 80.0% | 63.3% | 0/0 |
| R32 | 9 | Karen KhachanovHard | 27 | Nick KyrgiosHard | 6-7(3) 7-6(4) 6-2 | 3 | 133 | 13 | 3 | 68.4% | 83.1% | 56.7% | 3/4 |
| R32 | 3 | Roger FedererHard | 55 | Juan Ignacio LonderoHard | 6-3 6-4 | 3 | 61 | 9 | 0 | 66.0% | 77.1% | 83.3% | 1/1 |
| R32 | 70 | Andrey RublevHard | 23 | Stan WawrinkaHard | 6-4 6-4 | 3 | 83 | 0 | 0 | 54.3% | 63.2% | 75.0% | 5/5 |
| R32 | 8 | Daniil MedvedevHard | 29 | Benoit PaireHard | 7-6(2) 6-1 | 3 | 78 | 5 | 2 | 56.9% | 75.9% | 77.3% | 0/1 |
| R32 | 36 | Jan-Lennard StruffHard | 7 |  Stefanos TsitsipasHard | 6-4 6-7(5) 7-6(6) | 3 | 134 | 16 | 4 | 62.2% | 85.2% | 62.2% | 0/1 |
| R32 | 58 | Miomir KecmanovicHard | 6 | Alexander ZverevHard | 6-7(4) 6-2 6-4 | 3 | 138 | 3 | 3 | 66.3% | 74.6% | 40.6% | 3/6 |
| R32 | 11 | Roberto Bautista AgutHard | 52 | Frances TiafoeHard | 6-3 3-6 6-1 | 3 | 106 | 8 | 1 | 68.8% | 73.4% | 44.8% | 6/7 |
| R32 | 24 | Diego SchwartzmanHard | 39 | Radu AlbotHard | 6-4 6-2 | 3 | 91 | 3 | 4 | 72.1% | 84.1% | 29.4% | 5/5 |
| R32 | 56 | Richard GasquetHard | 66 | Federico DelbonisHard | 7-5 7-6(1) | 3 | 113 | 2 | 2 | 65.3% | 78.7% | 48.0% | 2/4 |
| R32 | 77 | Yoshihito NishiokaHard | 5 | Kei NishikoriHard | 7-6(2) 6-4 | 3 | 99 | 3 | 1 | 67.2% | 73.3% | 54.5% | 1/3 |
| R32 | 38 | Alex de MinaurHard | 42 | Reilly OpelkaHard | 7-6(3) 6-4 | 3 | 93 | 1 | 2 | 55.7% | 82.4% | 81.5% | 2/2 |
| R32 | 19 | David GoffinHard | 22 | Guido PellaHard | 6-1 7-5 | 3 | 86 | 4 | 2 | 65.5% | 76.3% | 45.0% | 6/7 |
| R32 | 59 | Adrian MannarinoHard | 46 |  Mikhail KukushkinHard | 6-1 6-3 | 3 | 76 | 9 | 2 | 46.4% | 76.9% | 53.3% | 6/7 |
| R16 | 1 | Novak DjokovicHard | 53 | Pablo Carreno BustaHard | 6-3 6-4 | 3 | 90 | 8 | 0 | 71.0% | 81.8% | 50.0% | 4/4 |
| R16 | 31 | Lucas PouilleHard | 9 | Karen KhachanovHard | 6-7(3) 6-4 6-2 | 3 | 118 | 9 | 5 | 60.0% | 75.0% | 60.0% | 2/2 |
| R16 | 70 | Andrey RublevHard | 3 | Roger FedererHard | 6-3 6-4 | 3 | 61 | 5 | 0 | 61.1% | 81.8% | 57.1% | 2/3 |
| R16 | 8 | Daniil MedvedevHard | 36 | Jan-Lennard StruffHard | 6-2 6-1 | 3 | 65 | 9 | 2 | 68.5% | 75.7% | 52.9% | 3/3 |
| R16 | 11 | Roberto Bautista AgutHard | 58 | Miomir KecmanovicHard | 6-1 6-2 | 3 | 59 | 6 | 2 | 76.0% | 76.3% | 50.0% | 2/2 |
| R16 | 56 | Richard GasquetHard | 24 | Diego SchwartzmanHard | 7-6(6) 6-3 | 3 | 107 | 11 | 4 | 54.8% | 75.0% | 57.6% | 1/2 |
| R16 | 77 | Yoshihito NishiokaHard | 38 | Alex de MinaurHard | 7-5 6-4 | 3 | 82 | 3 | 1 | 60.0% | 74.4% | 69.2% | 0/0 |
| R16 | 19 | David GoffinHard | 59 | Adrian MannarinoHard | 7-6(6) 6-2 | 3 | 96 | 4 | 2 | 55.9% | 81.8% | 57.7% | 0/1 |
| QF | 1 | Novak DjokovicHard | 31 | Lucas PouilleHard | 7-6(2) 6-1 | 3 | 86 | 5 | 6 | 71.4% | 88.9% | 38.9% | 3/3 |
| QF | 8 | Daniil MedvedevHard | 70 | Andrey RublevHard | 6-2 6-3 | 3 | 61 | 9 | 2 | 54.9% | 75.0% | 56.5% | 0/1 |
| QF | 56 | Richard GasquetHard | 11 | Roberto Bautista AgutHard | 7-6(2) 3-6 6-2 | 3 | 133 | 8 | 5 | 54.2% | 73.1% | 61.4% | 5/7 |
| QF | 19 | David GoffinHard | 77 | Yoshihito NishiokaHard | W/O | 3 | - | - | - | - | - | - | - |
| SF | 8 | Daniil MedvedevHard | 1 | Novak DjokovicHard | 3-6 6-3 6-3 | 3 | 102 | 16 | 4 | 67.9% | 78.2% | 42.3% | 1/2 |
| SF | 19 | David GoffinHard | 56 | Richard GasquetHard | 6-3 6-4 | 3 | 75 | 5 | 1 | 57.7% | 76.7% | 77.3% | 1/2 |
| F | 8 | Daniil MedvedevHard | 19 | David GoffinHard | 7-6(3) 6-4 | 3 | 99 | 10 | 1 | 52.6% | 90.0% | 63.0% | 2/3 |
