| R64 | 77 |  Roberto Carballes BaenaClay | 420 |  Andreas Haider-MaurerClay | 6-2 6-4 | 3 | 95 | 0 | 3 | 71.2% | 71.4% | 52.9% | 5/7 |
| R64 | 69 | Guillermo Garcia-LopezClay | 42 |  Yuichi SugitaClay | 7-6(5) 7-6(5) | 3 | 147 | 7 | 5 | 60.0% | 66.7% | 52.5% | 11/14 |
| R64 | 91 |  Dusan LajovicClay | 226 | Pedro MartinezClay | 6-4 6-7(5) 6-3 | 3 | 158 | 7 | 3 | 66.1% | 70.7% | 54.8% | 8/9 |
| R64 | 140 |  Martin KlizanClay | 76 |  Federico DelbonisClay | 6-3 6-7(5) 6-4 | 3 | 176 | 3 | 3 | 61.9% | 68.5% | 53.3% | 7/10 |
| R64 | 129 | Marcel GranollersClay | 95 |  Mikhail KukushkinClay | 6-2 6-2 | 3 | 66 | 5 | 0 | 53.8% | 90.5% | 72.2% | 0/0 |
| R64 | 45 | Leonardo MayerClay | 52 |  Mischa ZverevClay | 6-3 6-0 | 3 | 63 | 5 | 1 | 62.3% | 81.8% | 50.0% | 4/4 |
| R64 | 106 |  Bjorn FratangeloClay | 138 |  Alexey VatutinClay | 7-5 5-7 6-3 | 3 | 133 | 11 | 7 | 57.6% | 78.9% | 42.9% | 4/8 |
| R64 | 75 |  Ivo KarlovicClay | 211 | Tommy RobredoClay | 6-7(5) 7-6(8) 6-4 | 3 | 135 | 29 | 2 | 65.0% | 89.2% | 65.7% | 0/0 |
| R64 | 63 |  Stefanos TsitsipasClay | 137 |  Corentin MoutetClay | 6-4 6-1 | 3 | 87 | 2 | 3 | 60.3% | 71.1% | 48.0% | 3/5 |
| R64 | 125 |  Rogerio Dutra SilvaClay | 51 | Jared DonaldsonClay | 6-3 6-1 | 3 | 86 | 2 | 2 | 69.1% | 78.9% | 47.1% | 4/4 |
| R64 | 60 | Guido PellaClay | 50 | Peter GojowczykClay | 6-4 6-4 | 3 | 89 | 9 | 1 | 64.1% | 80.5% | 47.8% | 4/5 |
| R64 | 174 | Jaume MunarClay | 67 |  Joao SousaClay | 6-4 3-6 7-5 | 3 | 155 | 2 | 2 | 66.0% | 61.8% | 48.6% | 9/13 |
| R64 | 47 | Benoit PaireClay | 64 |  Nicolas JarryClay | 7-6(4) 6-7(3) 6-4 | 3 | 142 | 10 | 4 | 56.1% | 71.9% | 56.0% | 2/4 |
| R64 | 46 |  Pablo CuevasClay | 207 | Ricardo Ojeda LaraClay | 6-0 6-4 | 3 | 64 | 3 | 1 | 66.7% | 82.1% | 64.3% | 0/0 |
| R64 | 88 |  Malek JaziriClay | 49 | Tennys SandgrenClay | 6-4 6-4 | 3 | 94 | 2 | 0 | 52.3% | 70.6% | 71.0% | 3/3 |
| R64 | 70 | Gilles SimonClay | 117 |  Ilya IvashkaClay | 6-2 6-3 | 3 | 70 | 0 | 0 | 68.9% | 67.7% | 71.4% | 0/1 |
| R32 | 1 | Rafael NadalClay | 77 | Roberto Carballes BaenaClay | 6-4 6-4 | 3 | 111 | 1 | 0 | 62.9% | 66.7% | 60.9% | 3/5 |
| R32 | 69 | Guillermo Garcia-LopezClay | 22 | Kei NishikoriClay | 6-3 RET | 3 | 46 | 1 | 0 | 61.9% | 84.6% | 75.0% | 0/0 |
| R32 | 30 | Feliciano LopezClay | 91 | Dusan LajovicClay | 6-4 2-6 6-4 | 3 | 138 | 13 | 1 | 46.2% | 79.2% | 46.4% | 11/13 |
| R32 | 140 | Martin KlizanClay | 12 | Novak DjokovicClay | 6-2 1-6 6-3 | 3 | 99 | 4 | 4 | 62.7% | 66.7% | 60.0% | 2/4 |
| R32 | 10 |  David GoffinClay | 129 | Marcel GranollersClay | 4-6 7-6(2) 6-2 | 3 | 143 | 1 | 0 | 57.5% | 71.7% | 73.5% | 0/3 |
| R32 | 37 | Karen KhachanovClay | 45 | Leonardo MayerClay | 6-4 6-3 | 3 | 93 | 2 | 1 | 69.4% | 79.1% | 52.6% | 4/4 |
| R32 | 153 | Pablo AndujarClay | 106 | Bjorn FratangeloClay | 6-4 6-3 | 3 | 87 | 1 | 2 | 71.4% | 60.0% | 55.0% | 5/7 |
| R32 | 15 | Roberto Bautista AgutClay | 75 | Ivo KarlovicClay | 6-7(4) 6-2 6-4 | 3 | 117 | 1 | 3 | 64.2% | 90.4% | 58.6% | 1/1 |
| R32 | 63 | Stefanos TsitsipasClay | 17 | Diego SchwartzmanClay | 6-2 6-1 | 3 | 61 | 4 | 1 | 59.6% | 89.3% | 47.4% | 0/0 |
| R32 | 40 | Albert Ramos-VinolasClay | 125 | Rogerio Dutra SilvaClay | 3-6 6-3 6-4 | 3 | 134 | 4 | 4 | 65.4% | 76.5% | 55.6% | 2/4 |
| R32 | 146 | Jozef KovalikClay | 60 | Guido PellaClay | 6-3 6-3 | 3 | 80 | 1 | 1 | 61.4% | 74.3% | 68.2% | 5/5 |
| R32 | 7 | Dominic ThiemClay | 174 | Jaume MunarClay | 7-6(8) 6-1 | 3 | 89 | 9 | 4 | 68.9% | 88.1% | 52.6% | 0/1 |
| R32 | 11 | Pablo Carreno BustaClay | 47 | Benoit PaireClay | 6-3 6-3 | 3 | 63 | 2 | 2 | 67.2% | 76.9% | 52.6% | 1/1 |
| R32 | 27 | Adrian MannarinoClay | 46 | Pablo CuevasClay | 6-4 7-6(5) | 3 | 108 | 2 | 0 | 65.3% | 71.4% | 53.8% | 5/6 |
| R32 | 88 | Malek JaziriClay | 149 |  Ernesto EscobedoClay | 6-4 6-3 | 3 | 89 | 4 | 3 | 39.4% | 88.5% | 52.5% | 4/4 |
| R32 | 5 |  Grigor DimitrovClay | 70 | Gilles SimonClay | 6-2 6-1 | 3 | 82 | 3 | 5 | 49.1% | 70.4% | 60.7% | 3/3 |
| R16 | 1 | Rafael NadalClay | 69 | Guillermo Garcia-LopezClay | 6-1 6-3 | 3 | 79 | 0 | 0 | 54.3% | 60.0% | 66.7% | 0/1 |
| R16 | 140 | Martin KlizanClay | 30 | Feliciano LopezClay | 6-1 6-4 | 3 | 77 | 5 | 1 | 69.1% | 66.0% | 52.4% | 2/3 |
| R16 | 10 | David GoffinClay | 37 | Karen KhachanovClay | 2-6 7-6(2) 6-0 | 3 | 118 | 7 | 3 | 57.5% | 78.0% | 51.4% | 7/9 |
| R16 | 15 | Roberto Bautista AgutClay | 153 | Pablo AndujarClay | 6-4 6-1 | 3 | 79 | 1 | 0 | 64.7% | 63.6% | 66.7% | 2/4 |
| R16 | 63 | Stefanos TsitsipasClay | 40 | Albert Ramos-VinolasClay | 6-4 7-5 | 3 | 101 | 5 | 1 | 57.4% | 71.8% | 58.6% | 2/3 |
| R16 | 7 | Dominic ThiemClay | 146 | Jozef KovalikClay | 7-6(5) 6-2 | 3 | 103 | 4 | 5 | 47.9% | 58.8% | 59.5% | 5/8 |
| R16 | 11 | Pablo Carreno BustaClay | 27 | Adrian MannarinoClay | 6-2 4-6 7-6(6) | 3 | 158 | 3 | 1 | 64.6% | 59.4% | 57.1% | 2/7 |
| R16 | 5 | Grigor DimitrovClay | 88 | Malek JaziriClay | 7-5 3-6 7-6(8) | 3 | 169 | 7 | 7 | 63.7% | 70.8% | 54.1% | 3/7 |
| QF | 1 | Rafael NadalClay | 140 | Martin KlizanClay | 6-0 7-5 | 3 | 105 | 2 | 3 | 54.9% | 67.9% | 73.9% | 1/2 |
| QF | 10 | David GoffinClay | 15 | Roberto Bautista AgutClay | 6-7(3) 6-2 6-2 | 3 | 147 | 3 | 1 | 67.7% | 69.8% | 53.3% | 3/5 |
| QF | 63 | Stefanos TsitsipasClay | 7 | Dominic ThiemClay | 6-3 6-2 | 3 | 80 | 2 | 0 | 55.8% | 72.4% | 65.2% | 1/2 |
| QF | 11 | Pablo Carreno BustaClay | 5 | Grigor DimitrovClay | 6-3 7-6(4) | 3 | 97 | 0 | 0 | 66.7% | 65.2% | 60.9% | 3/5 |
| SF | 1 | Rafael NadalClay | 10 | David GoffinClay | 6-4 6-0 | 3 | 82 | 2 | 0 | 61.9% | 76.9% | 68.8% | 0/1 |
| SF | 63 | Stefanos TsitsipasClay | 11 | Pablo Carreno BustaClay | 7-5 6-3 | 3 | 95 | 5 | 0 | 59.7% | 77.5% | 51.9% | 0/1 |
| F | 1 | Rafael NadalClay | 63 | Stefanos TsitsipasClay | 6-2 6-1 | 3 | 78 | 0 | 3 | 71.4% | 77.1% | 42.9% | 3/3 |
