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| # | Player | First Tournament | First Date | Last Tournament | Last Date | Timespan |
|---|---|---|---|---|---|---|
| 1 |  Rafael Nadal | Roland Garros | 2005-05-23 | Roland Garros | 2022-05-23 | 6209 |
| 2 |  Novak Djokovic | Australian Open | 2008-01-14 | US Open | 2023-08-28 | 5705 |
| 3 |  Roger Federer | Wimbledon | 2003-06-23 | Australian Open | 2018-01-15 | 5320 |
| 4 |  Pete Sampras | US Open | 1990-08-27 | US Open | 2002-08-26 | 4382 |
| 5 | Andre Agassi | Wimbledon | 1992-06-22 | Australian Open | 2003-01-13 | 3857 |
| 6 |  Boris Becker | Wimbledon | 1985-06-24 | Australian Open | 1996-01-15 | 3857 |
| 7 | Jimmy Connors | Australian Open | 1973-12-26 | US Open | 1983-08-30 | 3534 |
| 8 |  Bjorn Borg | Roland Garros | 1974-06-03 | Roland Garros | 1981-05-25 | 2548 |
| 9 | Arthur Ashe | US Open | 1968-08-29 | Wimbledon | 1975-06-23 | 2489 |
| 10 | Stefan Edberg | Australian Open | 1985-11-25 | US Open | 1992-08-31 | 2471 |
| 11 | Mats Wilander | Roland Garros | 1982-05-24 | US Open | 1988-08-29 | 2289 |
| 12 | Ivan Lendl | Roland Garros | 1984-05-28 | Australian Open | 1990-01-15 | 2058 |
| 13 | John McEnroe | US Open | 1979-08-28 | US Open | 1984-08-28 | 1827 |
| 14 |  John Newcombe | Wimbledon | 1970-06-22 | Australian Open | 1974-12-26 | 1648 |
| 15 |  Marat Safin | US Open | 2000-08-28 | Australian Open | 2005-01-17 | 1603 |
| 16 |  Gustavo Kuerten | Roland Garros | 1997-05-26 | Roland Garros | 2001-05-28 | 1463 |
| 17 |  Andy Murray | US Open | 2012-08-27 | Wimbledon | 2016-06-27 | 1400 |
| 18 | Ken Rosewall | Roland Garros | 1968-05-27 | Australian Open | 1971-12-27 | 1309 |
| 19 |  Jan Kodes | Roland Garros | 1970-05-25 | Wimbledon | 1973-06-25 | 1127 |
| 20 | Carlos Alcaraz | US Open | 2022-08-29 | US Open | 2025-08-24 | 1091 |