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| # | Player | First Tournament | First Date | Last Tournament | Last Date | Timespan |
|---|---|---|---|---|---|---|
| 1 |  Novak Djokovic | Roland Garros | 2007-05-28 | US Open | 2025-08-24 | 6663 |
| 2 |  Jimmy Connors | Australian Open | 1973-12-26 | US Open | 1991-08-26 | 6452 |
| 3 | Andre Agassi | Roland Garros | 1988-05-23 | US Open | 2005-08-29 | 6307 |
| 4 |  Rafael Nadal | Roland Garros | 2005-05-23 | Wimbledon | 2022-06-27 | 6244 |
| 5 |  Roger Federer | Wimbledon | 2003-06-23 | Australian Open | 2020-01-20 | 6055 |
| 6 | John McEnroe | Wimbledon | 1977-06-20 | Wimbledon | 1992-06-22 | 5481 |
| 7 |  Marin Cilic | Australian Open | 2010-01-18 | Roland Garros | 2022-05-23 | 4508 |
| 8 | Pete Sampras | US Open | 1990-08-27 | US Open | 2002-08-26 | 4382 |
| 9 |  Wayne Ferreira | Australian Open | 1992-01-13 | Australian Open | 2003-01-13 | 4018 |
| 10 | Goran Ivanisevic | Wimbledon | 1990-06-25 | Wimbledon | 2001-06-25 | 4018 |
| 11 |  Boris Becker | Wimbledon | 1985-06-24 | Australian Open | 1996-01-15 | 3857 |
| 12 | Arthur Ashe | Wimbledon | 1968-06-24 | Australian Open | 1978-12-25 | 3836 |
| 13 | Tommy Haas | Australian Open | 1999-01-18 | Wimbledon | 2009-06-22 | 3808 |
| 14 | Ivan Lendl | Roland Garros | 1981-05-25 | US Open | 1991-08-26 | 3745 |
| 15 |  Tom Okker | US Open | 1968-08-29 | Wimbledon | 1978-06-26 | 3588 |
| 16 |  Juan Martin del Potro | Roland Garros | 2009-05-25 | US Open | 2018-08-27 | 3381 |
| 17 |  Jonas Bjorkman | US Open | 1997-08-25 | Wimbledon | 2006-06-26 | 3227 |
| 18 |  Andy Murray | US Open | 2008-08-25 | Roland Garros | 2017-05-29 | 3199 |
| 19 |  Ken Rosewall | Roland Garros | 1968-05-27 | Australian Open-1 | 1977-01-01 | 3141 |
| 20 |  Gael Monfils | Roland Garros | 2008-05-25 | US Open | 2016-08-29 | 3018 |