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| # | Player | First Tournament | First Date | Last Tournament | Last Date | Timespan |
|---|---|---|---|---|---|---|
| 1 |  Rafael Nadal | Roland Garros | 2005-05-23 | Roland Garros | 2022-05-23 | 6209 |
| 2 |  Novak Djokovic | US Open | 2007-08-27 | Wimbledon | 2024-07-01 | 6153 |
| 3 |  Roger Federer | Wimbledon | 2003-06-23 | Wimbledon | 2019-07-01 | 5852 |
| 4 |  Andre Agassi | Roland Garros | 1990-05-28 | US Open | 2005-08-29 | 5572 |
| 5 | Pete Sampras | US Open | 1990-08-27 | US Open | 2002-08-26 | 4382 |
| 6 |  Boris Becker | Wimbledon | 1985-06-24 | Australian Open | 1996-01-15 | 3857 |
| 7 | Jimmy Connors | Australian Open | 1973-12-26 | Wimbledon | 1984-06-25 | 3834 |
| 8 | Ivan Lendl | Roland Garros | 1981-05-25 | Australian Open | 1991-01-14 | 3521 |
| 9 |  Goran Ivanisevic | Wimbledon | 1992-06-22 | Wimbledon | 2001-06-25 | 3290 |
| 10 |  Juan Martin del Potro | US Open | 2009-08-31 | US Open | 2018-08-27 | 3283 |
| 11 |  Andy Murray | US Open | 2008-08-25 | Wimbledon | 2016-06-27 | 2863 |
| 12 |  Bjorn Borg | Roland Garros | 1974-06-03 | US Open | 1981-09-01 | 2647 |
| 13 | Michael Chang | Roland Garros | 1989-05-29 | US Open | 1996-08-26 | 2646 |
| 14 | Stefan Edberg | Australian Open | 1985-11-25 | Australian Open | 1993-01-18 | 2611 |
| 15 | Guillermo Vilas | Roland Garros | 1975-06-04 | Roland Garros | 1982-05-24 | 2546 |
| 16 | Arthur Ashe | US Open | 1968-08-29 | Wimbledon | 1975-06-23 | 2489 |
| 17 |  John Newcombe | Wimbledon | 1969-06-23 | Australian Open | 1975-12-26 | 2377 |
| 18 | Mats Wilander | Roland Garros | 1982-05-24 | US Open | 1988-08-29 | 2289 |
| 19 | Ken Rosewall | Roland Garros | 1968-05-27 | US Open | 1974-08-28 | 2284 |
| 20 | John McEnroe | US Open | 1979-08-28 | US Open | 1985-08-27 | 2191 |