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| Rank | Player | Reaches | Tournament |
|---|---|---|---|
| 1 |  Novak Djokovic | 21 | Australian Open |
| 2 |  Andre Agassi | 21 | US Open |
| 3 |  Roger Federer | 21 | Australian Open |
| 4 | Stan Wawrinka | 20 | Australian Open |
| 5 |  Gael Monfils | 20 | Australian Open |
| 6 |  Lleyton Hewitt | 20 | Australian Open |
| 7 |  Feliciano Lopez | 20 | US Open |
| 8 | Feliciano Lopez | 20 | Australian Open |
| 9 | Roger Federer | 19 | US Open |
| 10 |  Philipp Kohlschreiber | 19 | US Open |
| 11 | Novak Djokovic | 19 | US Open |
| 12 | Richard Gasquet | 19 | US Open |
| 13 | Fabrice Santoro | 18 | Australian Open |
| 14 | Fabrice Santoro | 18 | US Open |
| 15 | Fernando Verdasco | 18 | US Open |
| 16 | Rafael Nadal | 18 | Australian Open |
| 17 |  Andreas Seppi | 18 | US Open |
| 18 | Adrian Mannarino | 17 | Australian Open |
| 19 | Michael Chang | 17 | US Open |
| 20 | Tommy Haas | 17 | US Open |