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| Rank | Player | Reaches | Tournament |
|---|---|---|---|
| 1 |  Roger Federer | 21 | Australian Open |
| 2 |  Novak Djokovic | 20 | Roland Garros |
| 3 | Roger Federer | 19 | US Open |
| 4 | Novak Djokovic | 19 | Wimbledon |
| 5 | Novak Djokovic | 19 | US Open |
| 6 | Novak Djokovic | 18 | Australian Open |
| 7 | Roger Federer | 18 | Wimbledon |
| 8 |  Rafael Nadal | 18 | Roland Garros |
| 9 |  Jimmy Connors | 18 | US Open |
| 10 | Jimmy Connors | 17 | Wimbledon |
| 11 | Andre Agassi | 16 | US Open |
| 12 | Roger Federer | 16 | Roland Garros |
| 13 | Rafael Nadal | 16 | Australian Open |
| 14 |  Boris Becker | 14 | Wimbledon |
| 15 | Rafael Nadal | 14 | US Open |
| 16 | Pete Sampras | 13 | US Open |
| 17 |  Andy Murray | 13 | Wimbledon |
| 18 | Stan Wawrinka | 13 | US Open |
| 19 |  Guillermo Vilas | 13 | Roland Garros |
| 20 | John McEnroe | 13 | US Open |