| 2022-10-31 | Paris Masters | Hard | R64 | 16 |  Denis Shapovalov | 30 |  Francisco Cerundolo | 6-7(2) 6-3 6-4 | H2H | 3 | 132 | 9 | 3 | 57.3% | 78.4% | 63.2% | 1/2 |
| 2022-10-24 | Vienna | Hard | R16 | 12 |  Jannik Sinner (6) | 29 | Francisco Cerundolo | 7-5 6-3 | H2H | 3 | 89 | 2 | 0 | 64.6% | 64.3% | 60.9% | 2/4 |
| 2022-10-24 | Vienna | Hard | R32 | 29 | Francisco Cerundolo | 150 |  Filip Misolic (WC) | 6-3 6-3 | H2H | 3 | 68 | 4 | 1 | 45.8% | 86.4% | 69.2% | 1/1 |
| 2022-10-17 | Antwerp | Hard | R16 | 132 | Dominic Thiem (PR) | 28 | Francisco Cerundolo (6) | 6-1 1-6 7-5 | H2H | 3 | 127 | 3 | 0 | 70.5% | 63.6% | 65.2% | 2/5 |
| 2022-10-17 | Antwerp | Hard | R32 | 28 | Francisco Cerundolo (6) | 62 |  Marc-Andrea Huesler | 5-7 7-6(3) 6-3 | H2H | 3 | 139 | 7 | 5 | 66.0% | 78.8% | 47.1% | 2/4 |
| 2022-10-10 | Gijon | Hard | QF | 165 | Dominic Thiem (PR) | 29 | Francisco Cerundolo (4) | 6-4 6-3 | H2H | 3 | 93 | 2 | 0 | 74.1% | 70.0% | 42.9% | 1/3 |
| 2022-10-10 | Gijon | Hard | R16 | 29 | Francisco Cerundolo (4) | 153 |  Manuel Guinard (Q) | 7-6(5) 6-2 | H2H | 3 | 107 | 2 | 2 | 52.9% | 69.4% | 65.6% | 2/3 |
| 2022-10-03 | Astana | Hard | R32 | 10 |  Hubert Hurkacz (7) | 29 | Francisco Cerundolo | 6-2 7-6(2) | H2H | 3 | 80 | 11 | 0 | 77.6% | 80.0% | 69.2% | 1/1 |
| 2022-09-17 | Davis Cup Finals RR: ARG vs CRO | Hard | RR | 26 |  Borna Coric | 27 | Francisco Cerundolo | 6-4 7-6(6) | H2H | 3 | - | - | - | - | - | - | - |
| 2022-09-16 | Davis Cup Finals RR: ITA vs ARG | Hard | RR | 11 | Jannik Sinner | 27 | Francisco Cerundolo | 7-5 1-6 6-3 | H2H | 3 | - | - | - | - | - | - | - |
